Nonionic Surfactant Vesicles in Ocular Delivery: Innovative Approaches and Perspectives
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چکیده
منابع مشابه
Nonionic Surfactant Vesicles in Ocular Delivery: Innovative Approaches and Perspectives
With the recent advancement in the field of ocular therapy, drug delivery approaches have been elevated to a new concept in terms of nonionic surfactant vesicles (NSVs), that is, the ability to deliver the therapeutic agent to a patient in a staggered profile. However the major drawbacks of the conventional drug delivery system like lacking of permeability through ocular barrier and poor bioava...
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The respiratory system, as well as the skin, are organs in direct contact with the environment and they represent possible doors for the entrance of therapeutic agents into the body. Because of the increasing incidence of pulmonary diseases with high mortality and morbidity, pulmonary drug delivery is emerging as a non-invasive and attractive approach for the treatment of several pathologies. I...
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Nonionic surfactant vesicles (niosomes) were formulated with an aim of enhancing the oral bioavailability of tenofovir disoproxil fumarate (TDF), an anti-HIV drug. Niosomes were formulated by conventional thin film hydration technique with different molar ratios of surfactant, cholesterol, and dicetyl phosphate. The formulated niosomes were found spherical in shape, ranging from 2.95 μm to 10.9...
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Clouding phenomenon generally occurs with nonionic surfactants when the temperature of the system is raised to a certain value. This critical temperature is termed the cloud point (CP). The aqueous solutions of nonionic surfactants show complex phase behaviour including liquid-liquid phase separation at this temperature. The cloud point of aqueous surfactant solutions is influenced by the prese...
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Inflammatory processes play a crucial role in cardiovascular injury and disease. Inflamed endothelial cells express adhesion molecules which are potential therapeutic delivery targets for reducing or disrupting inflammation. We have developed non-ionic surfactant vesicles (niosomes) that are specifically targeted to inflamed vascular cells. Niosomes are self assembly vesicles that can encapsula...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2014
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2014/263604